- Communication -

Volume 4

Full article

PPD - Proteome Profile Database

Kishore R. Sakharkar¹ and Vincent T. K. Chow²*

¹ BioInformatics Institute, Singapore
² Human Genome Laboratory, Department of Microbiology, Faculty of Medicine, National University of Singapore, Kent Ridge, Singapore 117597
  Email: micctk@nus.edu.sg

*  corresponding author


Edited by E. Wingender; received December 24, 2003; revised and accepted February 23, 2004; published March 02, 2004

Abstract

With the complete sequencing of multiple genomes, there have been extensions in the methods of sequence analysis from single gene/protein-based to analyzing multiple genes and proteins simultaneously. Therefore, there is a demand of user-friendly software tools that will allow mining of these enormous datasets. PPD is a WWW-based database for comparative analysis of protein lengths in completely sequenced prokaryotic and eukaryotic genomes. PPD's core objective is to create protein classification tables based on the lengths of proteins by specifying a set of organisms and parameters. The interface can also generate information on changes in proteins of specific length distributions. This feature is of importance when the user's interest is focused on some evolutionarily related organisms or on organisms with similar or related tissue specificity or life-style. PPD is available at: PPD Home

Key words: protein length distribution, proteome, bioinformatics, genomics, obligatory intracellular parasites, genome, size, reduction, database, distribution, profile, classification, COG, KEGG, amino acid, composition, evolution, gene, organism life-style