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Volume 6


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In Silico Biology 6, 0055 (2006); ©2006, Bioinformation Systems e.V.  



MEGU: Pathway mapping web-service based on KEGG and SVG

Nobuaki Kono1, 2, Kazuharu Arakawa1,* and Masaru Tomita1, 2*

1 Institute for Advanced Biosciences, Keio University, Fujisawa, 252-8520, Japan
2 Department of Environmental Information, Keio University, Fujisawa, 252-8520, Japan


* Corresponding author
  Email: gaou@sfc.keio.ac.jp


Edited by E. Wingender; received November 14, 2006; revised and accepted November 30, 2006; published December 16, 2006


Abstract

Scientific visualization is a key technology to enhance our understanding of huge masses of omics data, especially for cell-wide, high-throughput measurements of the physiological networks. We have developed a web application that visualizes complex omics data of multiple layers simultaneously, including transcriptome, proteome, and metabolome, onto an integrated pathway diagram derived by connecting the individual KEGG pathway maps; the mapped images are generated in Scalable Vector Graphics for easy editing by hand or with computer programs or drawing software. The web application is available at http://megu.iab.keio.ac.jp/


Keywords: pathway visualization, omics, metabolism, web-service, KEGG