Topics to be covered by ISB (exemplary)
Organization of living systems:
Definition of molecular organization levels in living systemsGenomics:
Principles of genome organization revealed by computational methodsRelationship between genomic signals and biological functions
Genomic diversity of a species linked to certain phenotypes
Comparative genomics and genome evolution
Simulation of the function of gene networks
Proteins:
Secondary and tertiary structure prediction of proteinsStructure-function relationships of protein classes
Evaluation and prediction of protein-protein and protein-ligand interactions
Computer-aided discoveries in sequence and structure databases:
Modelling of biological reality in databasesEvaluation of sensitivity and selectivity of database searching methods
Novel protein and nucleic acid sequence and structural motifs associated with specific functions
Theory and practice of protein function prediction
Novel protein families and superfamily relationships uniting known families
Other topics:
Simulation of metabolic pathwaysPathological aberrations in regulatory networks